Operations Manual

The HRPP Operations Manual (OM) describes the overarching rules governing the University of Michigan’s Human Research Protection Program (HRPP) and serves as a policy and procedural reference for investigators, IRBs, administrators, and others.

The HRPP Operations Manual has 13 parts. It describes the overarching rules governing the University of Michigan’s Human Research Protection Program (HRPP) and outlines responsibilities, processes, and guidelines for the U-M investigators, the institutional review boards (IRBs), administrators, and others under the HRPP.

Last updated in April 2023.